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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE20
All Species:
8.79
Human Site:
S593
Identified Species:
24.17
UniProt:
Q9H1K0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1K0
NP_071735.2
784
88870
S593
P
K
T
P
S
L
S
S
T
Q
P
T
R
V
W
Chimpanzee
Pan troglodytes
XP_516306
784
88795
S593
P
K
T
P
S
P
S
S
T
Q
P
T
R
V
W
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541756
782
88486
S593
V
E
T
P
S
P
L
S
A
L
E
P
V
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y56
783
88473
S592
P
D
I
L
T
P
G
S
A
L
A
P
M
H
L
Rat
Rattus norvegicus
NP_001101345
783
88459
S592
P
D
I
L
S
P
G
S
A
L
A
P
I
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506047
760
86771
S578
L
D
A
P
Q
L
P
S
P
S
A
I
Q
E
S
Chicken
Gallus gallus
XP_414460
771
88823
Q583
F
E
T
T
A
V
Q
Q
L
P
A
K
E
Y
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697706
782
89918
R579
Q
A
E
E
Q
P
F
R
A
N
K
A
Q
Y
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392585
510
58583
I338
I
D
L
I
S
K
R
I
S
V
L
G
T
R
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
N.A.
90.4
N.A.
84
84.1
N.A.
72
67.5
N.A.
54.5
N.A.
N.A.
21.4
N.A.
N.A.
Protein Similarity:
100
99.4
N.A.
93.1
N.A.
89.6
89.5
N.A.
80.6
78.9
N.A.
69.5
N.A.
N.A.
39.6
N.A.
N.A.
P-Site Identity:
100
93.3
N.A.
26.6
N.A.
13.3
20
N.A.
20
6.6
N.A.
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
93.3
N.A.
33.3
N.A.
20
20
N.A.
26.6
26.6
N.A.
6.6
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
0
12
0
0
0
45
0
45
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% C
% Asp:
0
45
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
23
12
12
0
0
0
0
0
0
12
0
12
12
0
% E
% Phe:
12
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
23
0
0
0
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% H
% Ile:
12
0
23
12
0
0
0
12
0
0
0
12
12
0
0
% I
% Lys:
0
23
0
0
0
12
0
0
0
0
12
12
0
0
0
% K
% Leu:
12
0
12
23
0
23
12
0
12
34
12
0
0
0
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% N
% Pro:
45
0
0
45
0
56
12
0
12
12
23
34
0
0
0
% P
% Gln:
12
0
0
0
23
0
12
12
0
23
0
0
23
0
12
% Q
% Arg:
0
0
0
0
0
0
12
12
0
0
0
0
23
23
0
% R
% Ser:
0
0
0
0
56
0
23
67
12
12
0
0
0
0
12
% S
% Thr:
0
0
45
12
12
0
0
0
23
0
0
23
12
0
0
% T
% Val:
12
0
0
0
0
12
0
0
0
12
0
0
12
23
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _